Abstract

Case Report

Linear IgA bullous dermatosis in a child successfully responding to oral antibiotics

G Senhaji*, H Bay Bay, O El Jouari, A Lamouaffaq, Z Douhi, S Elloudi, FZ Mernissi and R Dassouli

Published: 06 December, 2018 | Volume 2 - Issue 1 | Pages: 008-011

Linear IgA bullous dermatosis (LABD) is a rare, chronic, autoimmune bullous dermatosis affecting young children and adults. The exact pathogenesis of this disease is still unknown, although both humoral and cellular immune response are involved. Clinically, it may show heterogeneous skin manifestations. However, it is characterized histologically by linear immunoglobulin A (IgA) deposits over the basal membrane, causing subepidermal blisters. Studies on LABD are relatively sparse and most of the publications are small series or single case reports. Several treatments are reported in literature, however, they should be used with care due to the risk of side effects. We report a case of linear IgA dermatosis with generalized lesions in a 7 year old child, with good outcome under dermocorticoids and antibiotics.

Read Full Article HTML DOI: 10.29328/journal.adr.1001005 Cite this Article Read Full Article PDF

Keywords:

Linear IgA bullous dermatosis; Autoimmune bullous dermatosis; Subepidermal blisters; Antibiotics

References

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