Linear IgA bullous dermatosis in a child successfully responding to oral antibiotics

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Submitted: November 15, 2018
Published: Dec 6, 2018
DOI: 10.29328/journal.adr.1001005
Keywords:
Linear IgA bullous dermatosis, Autoimmune bullous dermatosis, Subepidermal blisters, Antibiotics
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G Senhaji
Dermatology Department, University Hospital Hassan II, Fez, Morocco
H Bay Bay
Dermatology Department, University Hospital Hassan II, Fez, Morocco
R Dassouli
Dermatology Department, University Hospital Hassan II, Fez, Morocco
O El Jouari
Dermatology Department, University Hospital Hassan II, Fez, Morocco
A Lamouaffaq
Dermatology Department, University Hospital Hassan II, Fez, Morocco
Z Douhi
Dermatology Department, University Hospital Hassan II, Fez, Morocco
S Elloudi
Dermatology Department, University Hospital Hassan II, Fez, Morocco
FZ Mernissi
Dermatology Department, University Hospital Hassan II, Fez, Morocco

Abstract

Linear IgA bullous dermatosis (LABD) is a rare, chronic, autoimmune bullous dermatosis affecting young children and adults. The exact pathogenesis of this disease is still unknown, although both humoral and cellular immune response are involved. Clinically, it may show heterogeneous skin manifestations. However, it is characterized histologically by linear immunoglobulin A (IgA) deposits over the basal membrane, causing subepidermal blisters. Studies on LABD are relatively sparse and most of the publications are small series or single case reports. Several treatments are reported in literature, however, they should be used with care due to the risk of side effects. We report a case of linear IgA dermatosis with generalized lesions in a 7 year old child, with good outcome under dermocorticoids and antibiotics.

Article Details

Senhaji, G., Bay, H. B., Dassouli, R., Jouari, O. E., Lamouaffaq, A., Douhi, Z., … Mernissi, F. (2018). Linear IgA bullous dermatosis in a child successfully responding to oral antibiotics. Annals of Dermatological Research, 2(1), 008–011. https://doi.org/10.29328/journal.adr.1001005
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Copyright (c) 2018 Senhaji G, et al.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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