Case Report

Successful Treatment of Generalized Pustular Psoriasis during Pregnancy by Cyclosporin and Etanercept: Own Experience and Review of Literature

Rauno J Harvima* and Ilkka T Harvima

Published: 27 February, 2024 | Volume 8 - Issue 1 | Pages: 007-011

Psoriasis is a common inflammatory skin disease affecting about 2% of the population. Generalized pustular psoriasis (GPP) is a rare variant of this disease, and it can be life-threatening for a pregnant woman and fetus.
Medication during pregnancy can be challenging since many drugs can cause marked adverse effects for a fetus or newborn baby. Because controlled studies are difficult to perform, the knowledge grows slowly, e.g., from case reports. 
Here we describe a review of past and present treatments for GPP patients with a special reference to pregnancy and our experience on two GPP cases treated with cyclosporin and etanercept during pregnancy with successful outcomes of infants.

Read Full Article HTML DOI: 10.29328/journal.adr.1001032 Cite this Article Read Full Article PDF


Generalized pustular psoriasis; Pregnancy; Treatment


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