Abstract

Case Report

It is not invisible! A case report of 2 patients with scalp Lichen Planopilaris mimicking Androgenic Alopecia

Fabio Rinaldi*, Sorbellini Elisabetta, Pinto Daniela and Marzani Barbara

Published: 08 December, 2017 | Volume 1 - Issue 1 | Pages: 012-017

Lichen Planopilaris is known as the form of Lichen Planus typical of the scalp. It is classified as a lymphatic disease and is characterized by chronic inflammation which leads to cicatricial alopecia. Its causes are not yet well characterized but its etiology seems to strongly correlates with infection, sensitization and pollution. A clear and objective diagnosis of Lichen Planopilaris is not simple but the evolution and strongly negative outcomes on scalp of people affected by, pose the need of an early diagnosis.

In this work we report the case of a 27-year-old male and a 54-year-old female, respectively, in which a correct diagnosis of Lichen Planopilaris, followed the incorrect previous ones, was made by means of dermatoscopy and histopathological analysis, decisive tools for the diagnosis of this kind of pathology.

Read Full Article HTML DOI: 10.29328/journal.adr.1001003 Cite this Article Read Full Article PDF

References

  1. Assouly, Philippe; Reygagne, Pascal. Lichen planopilaris: update on diagnosis and treatment. Semin Cutan Med Surg. 2009; 28: 3-10. Ref: https://goo.gl/hQEsUa
  2. Pringle JJ. Lichen pilaris spinulosus. Br J Dermatol. 1905; 17: 78-97.
  3. Olsen EA, Bergfeld WF, Cotsarelis G, Price V, Shapiro R, et al. Workshop on cicatricial alopecia. Summary of North American Hair Research Society (NAHRS)-sponsored workshop on cicatricial alopecia, Duke University Medical Center, February 10 and 11, 2001. J Am Acad Dermatol. 2003; 48:103-110. Ref: https://goo.gl/2xKT8p
  4. Cooper S. Lichen planopilaris. Orphanet. 2011; Ref: https://goo.gl/DhtZSB
  5. Chieregato C, Zini A, Barba A, Magnanini M, Rosina P. Lichen planopilaris: report of 30 cases and review of the literature. Int J Dermatol. 2003; 42: 342-345. Review. Ref: https://goo.gl/S2xHx1
  6. Nathaniel C. Cevasco, Wilma F. Bergfeld, Berna K. Remzi, Haydee Ramirez de Knott. A case-series of 29 patients with lichen planopilaris: the Cleveland Clinic Foundation experience on evaluation, diagnosis, and treatment. J Am Acad Dermatol. 2007; 57: 47-53. Ref: https://goo.gl/QBGnmV
  7. Hoon Kang, Abdullateef A. Alzolibani, Nina Otberg, Jeery Shapiro. Lichen planopilaris. Dermatol Ther. 2008; 21: 249-256. Ref: https://goo.gl/EfGFqh
  8. Lehman JS, Tollefson MM, Gibson LE. Lichen planus. Int J Dermatol. 2009; 48: 682-694. Ref: https://goo.gl/FH4R2u
  9. Weston G, Payette M. Update on lichen planus and its clinical variants. Int J Womens Dermatol. 2015; 16:140-149. Ref: https://goo.gl/3oMJ1N
  10. Samrao A, Chew AL, Price V. Frontal fibrosing alopecia: a clinical review of 36 patients. Br J Dermatol. 2010; 163: 1296-1300. Ref: https://goo.gl/ivZ831
  11. Odom RB, James WD, Berger TG, editors. Andrews’ Diseases of the skin. 9th ed. Philadelphia: WB Saunders Elsevier, Lichen planus and related Conditions; pp. 2006; 274-275. Ref: https://goo.gl/M8FbAp
  12. Zinkernagel MS, Trüeb RM. Fibrosing alopecia in a pattern distribution: Patterned lichen planopilaris or androgenetic alopecia with a lichenoid tissue reaction pattern? Arch Dermatol. 2000; 136: 205-211. Ref: https://goo.gl/WVnqba
  13. Whiting D. Cicatricial alopecia: clinico-pathological findings and treatment. Clin Dermatol. 2001; 19: 211-225. Ref: https://goo.gl/72CpDr
  14. Mehregan DA, Van Hale HM, Muller SA. Lichen planopilaris: clinical and pathologic study of forty-five patients. J Am Acad Dermatol. 1992; 27: 935-942. Ref: https://goo.gl/iPJsYo
  15. Tan E, Martinka M, Ball N, Shapiro J. Primary cicatricial alopecias: clinicopathology of 112 cases☆. J Am Acad Dermatol. 2004; 50: 25-32. Ref: https://goo.gl/CJ7igP
  16. Tursen U, Api H, Kaya T, Ikizoglu G. Treatment of lichen planopilaris with mycophenolate mofetil. Dermatol Online J. 2004; 10: 24. Ref: https://goo.gl/BC6BNF
  17. Mirmirani P, Karnik P. Lichen planopilaris treated with a peroxisome proliferator-activated receptor gamma agonist. Arch Dermatol. 2009; 145: 1363-1366. Ref: https://goo.gl/ft26KW
  18. Reich A, Heisig M, Phan NQ, Taneda K, Takamori K, et al. Visual analogue scale: evaluation of the instrument for the assessment of pruritus. Acta Derm Venereol. 2012; 92: 497-501. Ref: https://goo.gl/JGdR1s
  19. Nirmal B, George R, Kodiatte TA. Invisible lichen planopilaris unmasked by dermatoscopy. Int J Trichol. 2017; 9: 76-78. Ref: https://goo.gl/Gt1VVB
  20. Grupper MC, Buisson J, Durepaire R, Edelson Y. [Gougerot's invisible lichen planus]. Bull Soc Fr Dermatol Syphiligr. 1971; 78: 598-599. French. Ref: https://goo.gl/B5eGVt
  21. d'Ovidio R, Sgarra C, Conserva A, Angelotti UF, Erriquez R, Foti C. Alterated integrin expression in lichen planopilaris. Head Face Med. 2007; 3: 11. Ref: https://goo.gl/PZrmkS
  22. Baquerizo Nole KL, Nusbaum B, Pinto GM, Miteva M. Lichen Planopilaris in the Androgenetic Alopecia Area: A Pitfall for Hair Transplantation. Skin Appendage Disorders. 2015; 1: 49-53. Ref: https://goo.gl/f7BmaQ
  23. Chiang C, Sah D, Cho BK, Ochoa BE, Price VH. Hydroxychloroquine and lichen planopilaris: efficacy and introduction of Lichen Planopilaris Activity Index scoring system. J Am Acad Dermatol. 2010; 62: 387-392. Ref: https://goo.gl/opaHBT
  24. Sorbellini E, Pinto D, Marzani B, Rinaldi F. Considerations about Lichen Planopilaris and the correct diagnosis. JPD. 2017.
  25. He Y, Gong D, Shi C, Shao F, Shi J, at. Dysbiosis of oral buccal mucosa microbiota in patients with oral lichen planus. Oral Dis. 2017; 23: 674-682. Ref: https://goo.gl/Mqv6Fo
  26. Srivastava K. Urbanization and mental health. Ind Psychiatry J. 2009; 18:75-76. Ref: https://goo.gl/7grFsr
  27. Dlova N, Goh CL, Tosti A. Familial frontal fibrosing alopecia. Br J Dermatol. 2012; 168: 220-2. Ref: https://goo.gl/7grFsr
  28. Bickers DR, Athar M. Oxidative stress in the pathogenesis of skin disease. J Invest Dermatol. 2006; 126: 2565-2575. Ref: https://goo.gl/xXW3TJ

Figures:

Figure 1

Figure 1

Figure 1

Figure 2

Figure 1

Figure 3

Figure 1

Figure 4

Figure 1

Figure 5

Figure 1

Figure 6

Similar Articles

Recently Viewed

Read More

Most Viewed

Read More

Help ?