It is not invisible! A case report of 2 patients with scalp Lichen Planopilaris mimicking Androgenic Alopecia
Article Sidebar
Main Article Content
Abstract
Lichen Planopilaris is known as the form of Lichen Planus typical of the scalp. It is classified as a lymphatic disease and is characterized by chronic inflammation which leads to cicatricial alopecia. Its causes are not yet well characterized but its etiology seems to strongly correlates with infection, sensitization and pollution. A clear and objective diagnosis of Lichen Planopilaris is not simple but the evolution and strongly negative outcomes on scalp of people affected by, pose the need of an early diagnosis.
In this work we report the case of a 27-year-old male and a 54-year-old female, respectively, in which a correct diagnosis of Lichen Planopilaris, followed the incorrect previous ones, was made by means of dermatoscopy and histopathological analysis, decisive tools for the diagnosis of this kind of pathology.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
Assouly, Philippe; Reygagne, Pascal. Lichen planopilaris: update on diagnosis and treatment. Semin Cutan Med Surg. 2009; 28: 3-10. Ref: https://goo.gl/hQEsUa
Pringle JJ. Lichen pilaris spinulosus. Br J Dermatol. 1905; 17: 78-97.
Olsen EA, Bergfeld WF, Cotsarelis G, Price V, Shapiro R, et al. Workshop on cicatricial alopecia. Summary of North American Hair Research Society (NAHRS)-sponsored workshop on cicatricial alopecia, Duke University Medical Center, February 10 and 11, 2001. J Am Acad Dermatol. 2003; 48:103-110. Ref: https://goo.gl/2xKT8p
Cooper S. Lichen planopilaris. Orphanet. 2011; Ref: https://goo.gl/DhtZSB
Chieregato C, Zini A, Barba A, Magnanini M, Rosina P. Lichen planopilaris: report of 30 cases and review of the literature. Int J Dermatol. 2003; 42: 342-345. Review. Ref: https://goo.gl/S2xHx1
Nathaniel C. Cevasco, Wilma F. Bergfeld, Berna K. Remzi, Haydee Ramirez de Knott. A case-series of 29 patients with lichen planopilaris: the Cleveland Clinic Foundation experience on evaluation, diagnosis, and treatment. J Am Acad Dermatol. 2007; 57: 47-53. Ref: https://goo.gl/QBGnmV
Hoon Kang, Abdullateef A. Alzolibani, Nina Otberg, Jeery Shapiro. Lichen planopilaris. Dermatol Ther. 2008; 21: 249-256. Ref: https://goo.gl/EfGFqh
Lehman JS, Tollefson MM, Gibson LE. Lichen planus. Int J Dermatol. 2009; 48: 682-694. Ref: https://goo.gl/FH4R2u
Weston G, Payette M. Update on lichen planus and its clinical variants. Int J Womens Dermatol. 2015; 16:140-149. Ref: https://goo.gl/3oMJ1N
Samrao A, Chew AL, Price V. Frontal fibrosing alopecia: a clinical review of 36 patients. Br J Dermatol. 2010; 163: 1296-1300. Ref: https://goo.gl/ivZ831
Odom RB, James WD, Berger TG, editors. Andrews’ Diseases of the skin. 9th ed. Philadelphia: WB Saunders Elsevier, Lichen planus and related Conditions; pp. 2006; 274-275. Ref: https://goo.gl/M8FbAp
Zinkernagel MS, Trüeb RM. Fibrosing alopecia in a pattern distribution: Patterned lichen planopilaris or androgenetic alopecia with a lichenoid tissue reaction pattern? Arch Dermatol. 2000; 136: 205-211. Ref: https://goo.gl/WVnqba
Whiting D. Cicatricial alopecia: clinico-pathological findings and treatment. Clin Dermatol. 2001; 19: 211-225. Ref: https://goo.gl/72CpDr
Mehregan DA, Van Hale HM, Muller SA. Lichen planopilaris: clinical and pathologic study of forty-five patients. J Am Acad Dermatol. 1992; 27: 935-942. Ref: https://goo.gl/iPJsYo
Tan E, Martinka M, Ball N, Shapiro J. Primary cicatricial alopecias: clinicopathology of 112 cases☆. J Am Acad Dermatol. 2004; 50: 25-32. Ref: https://goo.gl/CJ7igP
Tursen U, Api H, Kaya T, Ikizoglu G. Treatment of lichen planopilaris with mycophenolate mofetil. Dermatol Online J. 2004; 10: 24. Ref: https://goo.gl/BC6BNF
Mirmirani P, Karnik P. Lichen planopilaris treated with a peroxisome proliferator-activated receptor gamma agonist. Arch Dermatol. 2009; 145: 1363-1366. Ref: https://goo.gl/ft26KW
Reich A, Heisig M, Phan NQ, Taneda K, Takamori K, et al. Visual analogue scale: evaluation of the instrument for the assessment of pruritus. Acta Derm Venereol. 2012; 92: 497-501. Ref: https://goo.gl/JGdR1s
Nirmal B, George R, Kodiatte TA. Invisible lichen planopilaris unmasked by dermatoscopy. Int J Trichol. 2017; 9: 76-78. Ref: https://goo.gl/Gt1VVB
Grupper MC, Buisson J, Durepaire R, Edelson Y. [Gougerot's invisible lichen planus]. Bull Soc Fr Dermatol Syphiligr. 1971; 78: 598-599. French. Ref: https://goo.gl/B5eGVt
d'Ovidio R, Sgarra C, Conserva A, Angelotti UF, Erriquez R, Foti C. Alterated integrin expression in lichen planopilaris. Head Face Med. 2007; 3: 11. Ref: https://goo.gl/PZrmkS
Baquerizo Nole KL, Nusbaum B, Pinto GM, Miteva M. Lichen Planopilaris in the Androgenetic Alopecia Area: A Pitfall for Hair Transplantation. Skin Appendage Disorders. 2015; 1: 49-53. Ref: https://goo.gl/f7BmaQ
Chiang C, Sah D, Cho BK, Ochoa BE, Price VH. Hydroxychloroquine and lichen planopilaris: efficacy and introduction of Lichen Planopilaris Activity Index scoring system. J Am Acad Dermatol. 2010; 62: 387-392. Ref: https://goo.gl/opaHBT
Sorbellini E, Pinto D, Marzani B, Rinaldi F. Considerations about Lichen Planopilaris and the correct diagnosis. JPD. 2017.
He Y, Gong D, Shi C, Shao F, Shi J, at. Dysbiosis of oral buccal mucosa microbiota in patients with oral lichen planus. Oral Dis. 2017; 23: 674-682. Ref: https://goo.gl/Mqv6Fo
Srivastava K. Urbanization and mental health. Ind Psychiatry J. 2009; 18:75-76. Ref: https://goo.gl/7grFsr
Dlova N, Goh CL, Tosti A. Familial frontal fibrosing alopecia. Br J Dermatol. 2012; 168: 220-2. Ref: https://goo.gl/7grFsr
Bickers DR, Athar M. Oxidative stress in the pathogenesis of skin disease. J Invest Dermatol. 2006; 126: 2565-2575. Ref: https://goo.gl/xXW3TJ